What is PrEP

A once-daily pill that can change everything.

PrEP is one of the most powerful HIV prevention tools available today — and it's more accessible than you might think.

PrEP stands for Pre-Exposure Prophylaxis.

"Pre-exposure" means you take it before any potential exposure to HIV. "Prophylaxis" means prevention. Together, PrEP is a medication strategy that keeps HIV from taking hold in your body — even if you're exposed.

PrEP is not a cure for HIV, and it doesn't treat HIV. It's a prevention tool — taken daily by HIV-negative people who want to protect themselves.

Daily medication routine

How it works

One pill. Every day. Up to 99% protection.

01

Get tested first

Before starting PrEP, your doctor will confirm you're HIV-negative and check your kidney health. This is a simple blood test.

02

Take it daily

PrEP works best when taken every day at the same time. Consistency is key — the medication builds up in your body to provide protection.

03

Follow up every 3 months

Your provider will check in every 90 days to renew your prescription, re-test for HIV, and make sure everything is working well.

Effectiveness

The numbers speak for themselves.

99%

reduction in HIV risk from sex when taken daily

74%

reduction in HIV risk among people who inject drugs

2012

year the FDA first approved PrEP for HIV prevention

Effectiveness depends on consistent daily use. PrEP does not protect against other STIs — regular testing is still recommended.

Types of PrEP

Options that fit your life.

Truvada

The original daily oral PrEP pill, FDA-approved since 2012. Highly effective and widely available as a generic.

Descovy

A newer daily oral pill approved in 2019. Similar effectiveness with a slightly different safety profile — ask your provider which is right for you.

Apretude (CAB-LA)

A long-acting injectable PrEP given every two months by a healthcare provider. A great option if daily pills aren't your preference.

Cost & coverage

PrEP should be free — and often is.

Under the Affordable Care Act, most private insurance plans must cover PrEP with no out-of-pocket cost to you — including the medication, lab tests, and clinic visits.

Medicaid covers PrEP in Florida. If you're uninsured, the Ready, Set, PrEP program provides PrEP at no cost. Manufacturer assistance programs are also available.

Medical disclaimer

The information on this page is intended for educational purposes only and does not constitute medical advice. PrEP requires a prescription and ongoing medical supervision. Individual suitability, dosing, and monitoring requirements vary. Always consult a licensed healthcare provider before starting, stopping, or changing any medication or treatment. If you have questions about HIV prevention or PrEP, speak with a qualified clinician who can evaluate your specific health needs.

PREP Miami

Empowering Miami's community with the knowledge and access to HIV prevention tools — without judgment.

Medical Disclaimer: The information on this website is provided for educational purposes only and does not constitute medical advice. It is not a substitute for professional medical consultation, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you may have regarding a medical condition, medication, or treatment plan. Never disregard professional medical advice or delay seeking it because of something you have read on this site.

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